Bruce WainwrightBruce Wainwright

Olden wonder

THE CONSTANT PHARMA

Pharmaceutical companies have taken something of a kicking in recent months with the worldwide success of the movie The Constant Gardener.
Based on the novel by John Le Carré, and for the benefit of those who chose to go and see King Kong instead, the story involves the dubious ethical practices of a multinational drugs company eager
to get its latest blockbuster drug onto the market and none too scrupulous about the means of achieving this. After 40 years of writing intricate spy novels, Le Carré has moved onto new pastures. Smersh and the KGB having passed, we hope, into history; so Le Carré must necessarily find a new villain and his choice has fallen on the pharmaceutical industry.
Now to be perfectly fair to Le Carré, his creation in The Constant Gardener is an entirely fictitious confection, having no relationship to anything or anyone, living or dead. The drug company, Karel Vita Hudson, based in Switzerland, is not to be confused in any way with any other Swiss drugs company of a similar, or indeed dissimilar name.
Having said that, some of the shenanigans which the company becomes involved in do look unfortunately familiar to anyone who has even a passing knowledge of big pharmas. Dumping drugs which are beyond their sell-by date on medical charities in Africa in order to gain tax relief for charitable donations; failing to publish the less flattering findings of their research, and testing drugs on the third world’s poor are all too familiar to those who have observed the pharmaceutical industry’s history in the HIV epidemic over the last 20 years.
IllustrationHowever, it may be as well to remember which side our bread is buttered on. Without big pharma and the millions (or is it billions?) spent on the development of antiretrovirals, far too many of us, myself included, would now be dead, or, at the very least filling one of those beds now frequently empty and unused by Aids patients. One of the criticisms levelled in the past against the pharmaceutical companies is that too little research is carried out in areas such as Africa. This vastly expensive and lucrative activity is usually kept securely under the control of the parent company’s headquarters and testing is carried out elsewhere. The failure of pharmas to develop and produce drugs to tackle common tropical illnesses because the users don’t have the money to pay for them is well known, as is the battle to get affordable generic antiretrovirals past strict international patent laws. But profit and shareholder value is the name of the game. It isn’t about the brotherhood of man, or trying to do the decent thing; it’s profit. And to expect large corporations to ignore that is as unrealistic as expecting a leopard to turn vegetarian; it just isn’t going to happen and we have to keep that firmly in mind. If there was no profit in antiretrovirals, they would not be produced.
It is also worth noting that it is highly unlikely that anyone else would produce them either, governments included. Remember the good old USSR? The workers’ paradise? Completely incapable of producing a decent condom, it was common practice to use abortion as an all too regular form of contraception (anaesthetics available on payment of ‘blat’.) Pharmas may be motivated by profit but, thank goodness, it is motivated. Capitalism, much like democracy, stinks; until you look at the alternatives. Our job, I would suggest, is to do whatever we can to ensure that big pharmas behave more in accordance with our needs, and not theirs. It is possible.
Despite the very best endeavours of George W Bush and the naked commercial interests which pay his election expenses, the world order (whatever that might be) has managed to find a way around some of the patent laws and has made antiretrovirals cheaply, if not freely, available to a much wider public.
As a result, countries such as Brazil have succeeded in bringing their HIV epidemic under control with the free distribution of drugs.
Unlike Le Carré’s Karel Vita Hudson company, the real world is usually run by people with families who can, on occasions, be shamed into doing the right thing.

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