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cells within the fluid, even after two years on treatment. It has been
shown this type of virus can cause new infections in laboratory conditions.
However, the chemicals that stimulate HIV-infected cells to produce new
virus can be present in the vagina and urethra - so it could happen.
We do know that a minority - under five per cent - of men who have undetectable
viral loads in blood do have detectable virus in their semen.
More worryingly, a recent study showed that a third of women who had blood
viral loads under 400 had detectable virus - that means quite a bit more
than 400 - in their genital tract. Three-quarters of them were taking
combination therapy.
It's true that infection with low, but detectable, viral loads is rare
- one African survey reported no infections from anyone with a viral load
less than 1500. But some people may have much more virus than this in
their genital fluids - especially if they have a sexually-transmitted
infection (STI).
GC: So if one of the partners has an STI, they could become infected
or reinfect a partner with HIV when they couldn't before?
ST: Yes. People with STIs are both more infectious and more susceptible
to HIV infection. The study often quoted is one of men in Malawi. Those
that had urethritis inflammation of the urethra - due to STIs like chlamydia
or gonorrhoea had viral
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