Rebound was twice as likely for treatment-experienced patients
(59 per cent) compared with patients new to treatment (31 per
cent). Older patients were less likely to rebound, as were patients
with higher initial CD4 counts.
Mocroft concluded that the greatest risk of rebound appeared to
be in the first six months following initial viral suppression.
“Patients on more intensive regimens and those swapping
therapy were more likely to rebound, as were treatment-experienced
patients,” she said.
“Among experienced patients, those who had the option of
adding new drugs from the nucleoside group were at lower risk
of rebound.”
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| One
in 18 children in S. Africa has HIV |
 |
A new
study on HIV infection in South Africa has shown that children have
an infection rate of 5.6 per cent, leading to worries that South
Africa’s other epidemic - child abuse - is linked to the spread
of HIV.
The Nelson Mandela/Human Sciences Research Council (HSRC) study
of HIV and Aids - released earlier this month - drew for the first
time on a representative sample of the local population that included
all ages and population groups. Previous prevalence estimates have
been extrapolated from tests on particular groups such as pregnant
women or prisoners.
The new study, based on nearly 9,000 participants and using anonymous
saliva tests, has also shown that the white population is much more
at risk |
| from
the virus than previously thought - with around one in 16 - 6.2
per cent - carrying the virus.
But black Africans remained the group at most risk, carrying an
infection rate of 18.4 per cent.
Investigators are not sure why the prevalence among young children
is so high. Although abuse of children |
| is
common, it is not thought to be the whole explanation because abuse
is more common in girls than boys and yet the HIV rate was found
to be similar between the sexes. These results are |
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