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Hepatitis News

Hepatitis C treatment improves mental health

Successful treatment of hepatitis C (HCV) in patients both with and without HIV results in measurable improvements in mental agility, mental health and quality of life post-treatment, an Australian study has found.

Although deteriorations in mood and mental ability happened while patients were actually on treatment, these being well-known side-effects of interferon, these were back to normal six months later.

By this time cognitive function (mental ability) had bounced back to pre-treatment levels for the HCV patients and was considerably better than pre-treatment levels for the HCV/HIV patients.

Mental health in terms of depression, anxiety and stress was considerably better post-treatment than pre-treatment for the HCV mono-infected patients and back to pre-treatment levels, though not improved, for the HIV patients.

Given that HCV, HCV treatment and HIV all affect the brain, few studies have been done of the mental effects of HCV treatment. This was too small a study to tell us a lot, and larger studies are needed to see to what degree HCV treatment really does improve patients’ mental functioning.

• HIV Medicine 8(8), p 520-528.

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